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Image Search Results
Journal: International Journal of Molecular Sciences
Article Title: Lycopene Inhibits PRRSV Replication by Suppressing ROS Production
doi: 10.3390/ijms26157560
Figure Lengend Snippet: Lycopene inhibits PRRSV-induced inflammatory response. ( A , B ) PAM cells were infected with HP-PRRSV (MOI = 1) and treated with 10 μM of lycopene for 0–48 h. qRT-PCR analysis was conducted to evaluate the mRNA expression levels of IL-1β and IL-18 in the cells. *** p < 0.001; ** p < 0.01; * p < 0.05 (the p value is calculated vs. control). ( C , D ) PAM cells were infected with HP-PRRSV (MOI = 1) and treated with 10 μM of lycopene for 0–48 h. ELISA was used to measure the secretion levels of IL-1β and IL-18 in the cell supernatant. *** p < 0.001; ** p < 0.01; * p < 0.05 (the p value is calculated vs. control). ( E ) PAM cells were infected with PRRSV (MOI = 1) and treated with 10 μM of lycopene for 48 h. Immunoblotting was performed to analyze the levels of pro-caspase-1, caspase-1 P20, and GAPDH.
Article Snippet: The anti-GAPDH (10187-2-AP) and anti-dsRNA (85780-2-RR) antibodies were purchased from Proteintech (Rosemont, IL, USA), while the anti-Caspase-1 (sc-56036) and
Techniques: Infection, Quantitative RT-PCR, Expressing, Control, Enzyme-linked Immunosorbent Assay, Western Blot
Journal: Frontiers in Aging Neuroscience
Article Title: Oxytocin restores cognitive function and attenuates neuroinflammation in chronic sleep-deprived aged rats
doi: 10.3389/fnagi.2026.1742343
Figure Lengend Snippet: Bar graphs representing concentrations of neuroinflammatory markers, (A) NLRP3, (B) Caspase-1, (C) IL-1β, (D) TNF-α in brain tissue homogenates as measured by ELISA. * p < 0.05, ** p < 0.01 **** p < 0.0001 vs. control aged group, # p < 0.05, ## p < 0.01, ### p < 0.001, #### p < 0.0001 vs. oxytocin aged group, and $ p < 0.05, $$$ p < 0.001, $$$$ p < 0.0001 vs. sleep-deprived aged group.
Article Snippet: Levels of NLRP3 (antibodies, United States, A303739),
Techniques: Enzyme-linked Immunosorbent Assay, Control
Journal: Frontiers in Aging Neuroscience
Article Title: Oxytocin restores cognitive function and attenuates neuroinflammation in chronic sleep-deprived aged rats
doi: 10.3389/fnagi.2026.1742343
Figure Lengend Snippet: Multivariable analyses of all data sets after sleep deprivation and/or OXY intervention. (A) 3D plot of principal component analysis (PCA). (B) Variable importance score (VIP) scores declare the most influencing variable. (C) The correlation heatmap illustrates the inter-relationship among the studied variables. (D) Volcano plot among different groups. IL1B, interleukin 1B; MDA, malondialdehyde; Casp-1, Caspase-1; OXY, oxytocin; PCA, principal component analysis; Cortisone, Cortisone; Psen1, Presenilin-1; Htr2a, 5-hydroxytryptamine receptor 2A; NLRP3, Nucleotide-binding Oligomerization Domain-like Receptor Protein 3; TNF-α, tumor necrosis factor Alpha; VIP, Variable importance in projection.
Article Snippet: Levels of NLRP3 (antibodies, United States, A303739),
Techniques: Binding Assay